Hashimoto H, Shiokawa Y
J Rheumatol. 1982 May-Jun;9(3):386-9.
The changing patterns of clinical features and prognosis of 307 Japanese patients with systemic lupus erythematosus (SLE) were studied. SLE patients with Raynaud's phenomenon, alopecia and oral ulceration increased significantly in Group B (1970-1979) compared to Group A (1955-1969). It was noted that SLE patients with LE cells were significantly fewer in Group B and in Group A. The prognosis of Group B was significantly improved over that of Group A. There was a significant decline in deaths caused by uremia and central nervous system lupus in Group B.
对307例日本系统性红斑狼疮（SLE）患者的临床特征和预后变化模式进行了研究。与A组（1955 - 1969年）相比，B组（1970 - 1979年）中出现雷诺现象、脱发和口腔溃疡的SLE患者显著增加。值得注意的是，B组和A组中出现狼疮细胞的SLE患者明显较少。B组的预后明显优于A组。B组中由尿毒症和中枢神经系统狼疮导致的死亡显著下降。
