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[杏仁核复合体变化作用下主动脉壁的肾上腺激素水平与胶原代谢]

[Adrenal hormone level and collagen metabolism in the aortic wall under the effect of changes in the amygdaloid complex].

作者信息

Butolin E G, Danilov G E, Sharaev P N

出版信息

Probl Endokrinol (Mosk). 1982 Jul-Aug;28(4):59-62.

PMID:7122448
Abstract

The blood catecholamine, 11-hydroxycorticosteroid and free hydroxyproline content and collagen metabolism in the rabbit aortic wall were studied under conditions of chronic electrostimulation and bilateral amygdaloid electrocoagulation. It was found that electrostimulation of the amygdaloid lateral nucleus causes changes in the adrenocorticotropin content, activating collagen metabolism and accumulation in the aortic wall. A fall of the noradrenaline, 11-hydroxycorticosteroid concentration and activation of collagen metabolism, accompanied by its accumulation in the aortic wall, are seen during the 1st month after electrocoagulation.

摘要

研究了慢性电刺激和双侧杏仁核电凝条件下家兔主动脉壁中血液儿茶酚胺、11-羟皮质类固醇和游离羟脯氨酸含量以及胶原代谢情况。发现电刺激杏仁核外侧核会导致促肾上腺皮质激素含量发生变化,激活胶原代谢并使其在主动脉壁中蓄积。电凝后第1个月可观察到去甲肾上腺素、11-羟皮质类固醇浓度下降以及胶原代谢激活,并伴有其在主动脉壁中的蓄积。

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