Charles E S, Rao K V, Sharma S
Pharmazie. 1982 Jun;37(6):413-5.
The synthesis and biological activity of a series of substituted benzamides (5-8, 14-17) 3,5-dinitrobenzoic acids (12, 13, 18) and benzimidazoles (9-11, 19-21) are described. Compounds 5, 6, 7, 12 and 14 showed 40-50% clearance of Nippostrongylus brasiliensis in rats at a dose of 250 mg/kg given daily for 3 d while a few compounds inhibited the growth of various strains of bacteria and fungi.
描述了一系列取代苯甲酰胺（5 - 8、14 - 17）、3,5 - 二硝基苯甲酸（12、13、18）和苯并咪唑（9 - 11、19 - 21）的合成及生物活性。化合物5、6、7、12和14在以250 mg/kg的剂量每日给药3天的情况下，对大鼠体内的巴西日圆线虫显示出40 - 50%的清除率，同时有几种化合物抑制了多种细菌和真菌菌株的生长。
