Stoynev A G, Ikonomov O C, Usunoff K G
Physiol Behav. 1982 Jul;29(1):35-40. doi: 10.1016/0031-9384(82)90362-6.
Bilateral destruction of the suprachiasmatic nuclei (SCN) eliminated light-dark (L/D) variations in water intake and urine output in albino rats. The lesions abolished also the circadian rhythm of food intake, without changing significantly the 24 hour number of meals, total meal duration and 24 hour food intake. Only the L/D distribution of the number of meals was changed from 5.6/16.9 in control period to 12.7/12.9 after lesions. In contrast, the L/D distribution of sodium, potassium and chlorides excretions demonstrated attenuated but persistent nocturnal type. These data imply that SCN play a role of driving oscillator for the circadian rhythm of food intake, but probably are not the main synchronizer for the rhythms of electrolyte excretions.
双侧损毁白化大鼠的视交叉上核（SCN）可消除其饮水和尿量的明暗（L/D）变化。损伤还消除了食物摄入的昼夜节律，而24小时进餐次数、总进餐时长和24小时食物摄入量均无显著变化。仅进餐次数的L/D分布从对照期的5.6/16.9变为损伤后的12.7/12.9。相比之下，钠、钾和氯化物排泄的L/D分布呈现出减弱但持续的夜间类型。这些数据表明，SCN在食物摄入昼夜节律中起驱动振荡器的作用，但可能不是电解质排泄节律的主要同步器。
