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[不同年龄家兔血清及肝脏白蛋白的氨基酸组成]

[Amino acid composition of serum and liver albumin in rabbits of different ages].

作者信息

Ostolovskiĭ E M

出版信息

Zh Evol Biokhim Fiziol. 1982 Jul-Aug;18(4):422-5.

PMID:7124207
Abstract

Studies have been made on the molecular weight and amino acid composition of albumin from the blood serum and liver, as well as on its content in liver extracts and in the blood serum of male rabbits at the age of 1, 30, 180, and 720 days. During postnatal life, quantitative changes in the amino acid composition of the proteins investigated take place, which are more significant in liver albumin than in serum albumin. Albumin content of the blood serum and liver extracts decreases at later ontogenetic stages (in 180- and 720-day animals), which is presumably associated with the decrease in synthesis of this protein by the liver. The molecular weight of the albumin remains constant in all age groups being typical for serum albumin of vertebrates.

摘要

已经对雄性兔子在1日龄、30日龄、180日龄和720日龄时血清和肝脏中白蛋白的分子量、氨基酸组成以及肝脏提取物和血清中的含量进行了研究。在出生后的生命过程中,所研究蛋白质的氨基酸组成发生了定量变化,肝脏白蛋白中的变化比血清白蛋白中的变化更为显著。血清和肝脏提取物中的白蛋白含量在个体发育后期(180日龄和720日龄动物)有所下降,这可能与肝脏中该蛋白质合成的减少有关。白蛋白的分子量在所有年龄组中均保持恒定,这是脊椎动物血清白蛋白的典型特征。

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