[Differential-diagnostic possibilities of the morphologic dissociation reaction of clotted blood in the acute period of strokes].

The authors studied for the first time changes in the parameters of the coagulated blood morphological dissociation test (CBMDT) in 234 patients with stroke in the most acute period. They revealed a stable dependence between the character and extent of the changes in the CBMDT and the form and severity of the stroke and the time course of the pathological process. Changes in the main CBMDT parameters in hemorrhagic stroke were diametrically opposite to those in ischemic stroke: an increase in the volume and the time of formation of three blood coagulation fractions (TBCF) was revealed in hemorrhave and, on the contrary, a decrease in the TBCF value and the time of its precipitation in ischemia. The extent of these shifts was determined by the severity of the disease. According to the authors' findings severe forms of stroke differ in the TBCF volume in 96% of cases and in the time of sedimentation in 81%. In a moderately severe stroke the respective figures were 15 and 79% and in diseases following a satisfactory course in 9 and 74% of cases. The severity of the pathological process may be judged by and its time course studied from the changes in the CBMDT parameters.