Günther J, Storch E, Vetter R
Acta Biol Med Ger. 1982;41(4):333-9.
To characterize consequences of rape oil-induced changes on the Ca regulation in rabbit papillary muscle, the influence of increasing extracellular Ca (Cae) on contraction, relaxation and resting potentiation of tension has been investigated after a 12 weeks lasting rape oil-diet. After oil diet increasing Cae caused a similar augmentation in peak tension T accompanied by an increased index in contractility [Formula: see text], a significantly shortened time to peak tension and a decline in refractory period. A higher relaxation rate is demonstrated by the maximum relaxation rate [Formula: see text], the half time of relaxation RT 1/2 and relaxation time RT. The resting potentiation of the isometric contraction was enhanced. The results are in agreement with the assumption that the sarcoplasmic reticulum (SR) is more involved in Ca regulation after the oil diet than in the control group. This may be related to differences in the phospholipid content of SR membranes.
为了描述菜籽油诱导的变化对兔乳头肌钙调节的影响，在持续12周的菜籽油饮食后，研究了增加细胞外钙（Cae）对张力收缩、舒张和静息增强的影响。油饮食后增加Cae导致峰值张力T有类似的增加，同时收缩性指数[公式：见正文]增加，达到峰值张力的时间显著缩短，不应期缩短。最大舒张率[公式：见正文]、舒张半衰期RT 1/2和舒张时间RT表明舒张率更高。等长收缩的静息增强。结果与以下假设一致，即与对照组相比，油饮食后肌浆网（SR）在钙调节中发挥更大作用。这可能与SR膜磷脂含量的差异有关。
