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[β-拟交感神经药的产热作用]

[Calorigenic action of beta-sympathomimetics].

作者信息

Ankermann H

出版信息

Acta Biol Med Ger. 1982;41(4):377-84.

PMID:7124255
Abstract

In experiments on narcotized rats it has been demonstrated that not only isoprenaline and orciprenaline but terbutaline, salbutamol and clenbuterol as well have calorigenic effects. The effectiveness is regressing considerably from isoprenaline over orciprenaline, salbutamol and terbutaline. Clenbuterol, too, has essentially weaker calorigenic effects than isoprenaline. The duration of calorigenic effects rise clearly from isoprenaline over orciprenaline, terbutaline, salbutamol and clenbuterol, while this effect is beginning more hesitatingly in the same order of these substances.

摘要

在对麻醉大鼠的实验中已证明,不仅异丙肾上腺素和奥西那林,而且特布他林、沙丁胺醇和克仑特罗也有产热作用。从异丙肾上腺素到奥西那林、沙丁胺醇和特布他林,其效力显著递减。克仑特罗的产热作用也明显弱于异丙肾上腺素。产热作用的持续时间从异丙肾上腺素到奥西那林、特布他林、沙丁胺醇和克仑特罗明显增加,而这些物质以相同顺序产生这种作用时开始得较为迟缓。

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