Konno A, Togawa K, Nishihira S
Acta Otolaryngol. 1982 Jul-Aug;94(1-2):131-40. doi: 10.3109/00016488209128897.
A study was performed to evaluate whether vascular reflex participates in mucosal swelling in nasal allergy, by measuring changes in mucosal swelling in both nasal cavities and changes in blood flow in the bilateral inferior turbinates caused by antigenic challenge in one inferior turbinate. On unilateral challenge, the mucosa of the ipsilateral nasal cavity became swollen, with a concomitant increase in mucosal blood flow. In the contralateral nasal cavity, however, an increase in mucosal blood flow was not necessarily accompanied by mucosal swelling. An increase in mucosal blood flow on antigenic challenge was observed even in nasal mucosa, most of the parasympathetic and sympathetic innervation to which was transected by vidian neurectomy. Vascular reflex certainly participates in nasal allergy but it is not always related to mucosal swelling. Mucosal swelling in nasal allergy is considered to be caused mainly by a direct effect of chemical mediators on nasal vasculature and partly by vascular reflex.
通过测量一侧下鼻甲抗原激发后双侧鼻腔黏膜肿胀的变化以及双侧下鼻甲血流的变化，进行了一项研究以评估血管反射是否参与鼻变态反应中的黏膜肿胀。单侧激发时，同侧鼻腔黏膜肿胀，同时黏膜血流增加。然而，在对侧鼻腔，黏膜血流增加并不一定伴有黏膜肿胀。即使在大部分副交感神经和交感神经支配已被岩大神经切断的鼻黏膜中，抗原激发时仍可观察到黏膜血流增加。血管反射肯定参与鼻变态反应，但它并不总是与黏膜肿胀相关。鼻变态反应中的黏膜肿胀被认为主要由化学介质对鼻血管的直接作用引起，部分由血管反射引起。
