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美国士兵病毒性肝炎的病因

Etiology of viral hepatitis in American soldiers.

作者信息

Lemon S M, Lednar W M, Bancroft W H, Cannon H G, Benenson M, Park J H, Churchill F E, Tezak R W, Erdtmann F J, Kirchdoerfer R G, Lewis P G, James J J, Miller R N

出版信息

Am J Epidemiol. 1982 Sep;116(3):438-50. doi: 10.1093/oxfordjournals.aje.a113428.

DOI:10.1093/oxfordjournals.aje.a113428
PMID:7124711
Abstract

To define better which types of hepatitis are prevalent among American soldiers, the authors studied 413 separate episodes of acute viral hepatitis among 412 soldiers admitted to US Army hospitals during 1978-1979. Most soldiers (68.8%) had acute hepatitis B (estimated annual hospitalization rate: 5.41/1000 soldiers in West Germany, 2.51/1000 in South Korea, less than 1/1000 in the United States). Subtype ayw was predominant in Germany, whereas adr was predominant in South Korea. Hepatitis B was more often associated with contact history or parenteral use of drugs in West Germany than in South Korea (p less than 0.001). Non-A, non-B hepatitis accounted for 27% of cases in West Germany (2.16/1000), but only 3% in South Korea (0.11/1000); hepatitis A only 15% in South Korea (0.48/1000) and 1% in West Germany (0.08/1000). These findings indicate that hepatitis B is the most prevalent form of viral hepatitis among US soldiers worldwide but also suggest substantial differences in the epidemiology of this infection in South Korea and West Germany. Such data will be useful in developing hepatitis B immunization policy within the military.

摘要

为了更确切地确定在美国士兵中流行的肝炎类型,作者对1978年至1979年期间入住美国陆军医院的412名士兵中的413例急性病毒性肝炎单独病例进行了研究。大多数士兵(68.8%)患有急性乙型肝炎(估计年住院率:在西德为5.41/1000名士兵,在韩国为2.51/1000,在美国低于1/1000)。ayw亚型在德国占主导地位,而adr亚型在韩国占主导地位。与韩国相比,西德的乙型肝炎更常与接触史或非肠道用药有关(p<0.001)。非甲非乙型肝炎在西德占病例的27%(2.16/1000),但在韩国仅占3%(0.11/1000);甲型肝炎在韩国仅占15%(0.48/1000),在西德占1%(0.08/1000)。这些发现表明,乙型肝炎是全球美国士兵中最普遍的病毒性肝炎形式,但也表明这种感染在韩国和西德的流行病学存在很大差异。这些数据将有助于制定军队中的乙型肝炎免疫政策。

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Etiology of viral hepatitis in American soldiers.美国士兵病毒性肝炎的病因
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