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德国纽伦堡的乙型肝炎。一种与药物相关的流行病的流行病学。在美国陆军士兵中。

Hepatitis B in Nuremberg, Germany. Epidemiology of a drug-associated epidemic. Among US Army soldiers.

作者信息

Cates W, Warren J W

出版信息

JAMA. 1975 Dec 1;234(9):930-4. doi: 10.1001/jama.234.9.930.

Abstract

Beginning in 1971, acute viral hepatitis was epidemic among US soldiers stationed in Europe, with a total of over 8,700 cases reported between 1971 and 1974. Hepatitis B surface antigen (HBsAg) determinations suggest a predominance of hepatitis B. In the Nuremberg area, primary association was with the illicit use of drugs. This association was demonstrated by a chronologic relationship between measurable community drug use and the number of hepatitis admissions three to six months later and by a case-control study. Parenteral drug use and, to a lesser degree, cannabis smoking appeared to be factors in disease transmission. Sharing of illicit drugs with a hepatitis contact, whether parenterally or orally, was associated with increased risk of contracting the disease.

摘要

从1971年开始,急性病毒性肝炎在驻扎在欧洲的美国士兵中流行,1971年至1974年间共报告了8700多例病例。乙肝表面抗原(HBsAg)检测表明乙肝占主导。在纽伦堡地区,主要与非法使用药物有关。这种关联通过可测量的社区药物使用与三到六个月后肝炎住院人数之间的时间关系以及一项病例对照研究得以证实。注射吸毒以及程度较轻的吸食大麻似乎是疾病传播的因素。与肝炎患者接触者共用非法药物,无论是通过注射还是口服,都与感染该疾病的风险增加有关。

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