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冰岛甲型肝炎抗体流行情况与年龄、性别及甲型肝炎报告病例数的关系。

Prevalence of antibody to hepatitis A in Iceland in relation to age, sex, and number of notified cases of hepatitis.

作者信息

Briem H, Weiland O, Fridriksson I, Berg R

出版信息

Am J Epidemiol. 1982 Sep;116(3):451-5. doi: 10.1093/oxfordjournals.aje.a113429.

DOI:10.1093/oxfordjournals.aje.a113429
PMID:7124712
Abstract

The prevalence of antibody to hepatitis A virus (anti-HAV) was investigated in 623 outpatients in Iceland. No difference in anti-HAV prevalence according to sex or rural vs. urban residence was found. The prevalence rates in different age groups were found to be comparable to those in the Scandinavian countries, increasing from 1.6% (1/63) in persons below 20 years of age to 66% (51/77) in persons above 60 years of age. The numbers of notified cases of hepatitis (epidemic jaundice) in Iceland during the 20th century showed a pattern of repeated epidemics up to the early 1950s, after which low rates were noted. The incidence of hepatitis dropped 30-fold during the 20th century. Persons born after the latest epidemic in 1952 were positive for anti-HAV in only 4.7% (7/150).

摘要

对冰岛623名门诊患者进行了甲型肝炎病毒抗体(抗-HAV)流行情况调查。未发现抗-HAV流行率在性别或城乡居住方面存在差异。不同年龄组的流行率与斯堪的纳维亚国家的情况相当,从20岁以下人群中的1.6%(1/63)增至60岁以上人群中的66%(51/77)。20世纪冰岛报告的肝炎(流行性黄疸)病例数显示,直至20世纪50年代初呈现反复流行的模式,此后发病率较低。20世纪肝炎发病率下降了30倍。在1952年最近一次流行之后出生的人抗-HAV阳性率仅为4.7%(7/150)。

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