Studies on the genetic and non-genetic (physiological) variation of human erythrocyte glutamic oxaloacetic transaminase.

The thermostability profile of seven different electrophoretic variants of human erythrocyte GOT found in 13 different, unrelated families from a racially heterogeneous population was examined. The five different slow-variant and the two different fast-variant classes could be grouped into four different thermostability classes which were termed unstable, less stable, normal and more stable than normal. The thermostability differences among and within the electrophoretic variant classes permitted differentiation of the 13 individuals possessing an electrophoretic variant phenotype into a total of ten different variants.