胃旁路手术与胃分隔术治疗病态肥胖的疗效比较：远端胃和十二指肠旷置的影响
The effectiveness of gastric bypass over gastric partition in morbid obesity: consequence of distal gastric and duodenal exclusion.
作者信息
Pories W J, Flickinger E G, Meelheim D, Van Rij A M, Thomas F T
出版信息
Ann Surg. 1982 Oct;196(4):389-99. doi: 10.1097/00000658-198210000-00002.
Eighty-seven morbidly obese patients were prospectively randomized to two operations: gastric bypass was performed on 42 and gastric partition on 45. Gastric bypass proved to be more effective; gastric bypass patients lost 15% more of their original weight at 12 months and 21% more at 18 months. There were no failures in the gastric bypass group; 28 of the 45 operations failed in the gastric partition group. An additional 60 patients underwent gastric bypass since the completion of the study. In the total series of 147 patients who underwent gastric bypass or gastric partition, there was no mortality, and the surgical complication rate was 12%. Because the gastric pouches and the anastomoses were similar in the two operations, the superiority of the gastric bypass may well be due to a heretofore unexplained effect of distal gastric and duodenal exclusion.
87例病态肥胖患者被前瞻性随机分为两组进行手术：42例行胃旁路手术，45例行胃分隔术。结果表明胃旁路手术更有效；胃旁路手术患者在12个月时体重减轻比原来多15%，在18个月时多21%。胃旁路手术组无手术失败病例；胃分隔术组45例手术中有28例失败。自研究完成后，另有60例患者接受了胃旁路手术。在总共147例行胃旁路手术或胃分隔术的患者中，无死亡病例，手术并发症发生率为12%。由于两种手术中的胃囊和吻合口相似，胃旁路手术的优越性很可能归因于远端胃和十二指肠旷置的一种迄今无法解释的效应。
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