Janik J S, Nagaraj H S, Groff D B
Arch Surg. 1982 Oct;117(10):1321-4. doi: 10.1001/archsurg.1982.01380340047011.
The appearance and severity of peritoneal adhesions after simple laparotomy and after adhesiolysis were studied in a rabbit model. Adhesions were induced by direct abrasion with latex glove and dry gauze; control rabbits had abrasion only. Study groups had abrasion and treatment with 10% or 25% povidone. Results showed a significant reduction in the number of adhesions and in the severity of adhesions after treatment with povidone. This study supports the further investigation of the efficacy of povidone in preventing postoperative peritoneal adhesions.
在兔模型中研究了单纯剖腹术后和粘连松解术后腹膜粘连的外观和严重程度。通过用乳胶手套和干纱布直接摩擦诱导粘连；对照兔仅进行摩擦。研究组进行摩擦并使用10%或25%的聚维酮治疗。结果显示，聚维酮治疗后粘连数量和粘连严重程度显著降低。本研究支持进一步研究聚维酮预防术后腹膜粘连的疗效。
