Golding S J, Husband J E
Br J Radiol. 1982 Oct;55(658):740-7. doi: 10.1259/0007-1285-55-658-740.
Seventy-seven patients with soft tissue sarcoma underwent computed tomography (CT) between 1977 and 1981. The results have been analysed to determine the characteristics of these tumours on CT, the accuracy of CT in predicting resectability and in the detection of distant metastases, and the influence of CT findings on patient management. The majority of tumours appeared as masses which were well-defined, either by surrounding soft tissue planes or because the tumour had a significantly different attenuation value to the surrounding tissues. No correlation was found between the characteristics on CT and the tumour histology. A prediction of operability based on the CT appearances was compared with the surgical findings in 24 patients. This prediction was correct in 22 patients (92%) and further useful surgical information was provided in 11 patients (46%). A comparison of the CT findings with those of chest radiography, including whole lung tomography, showed that CT demonstrated a significantly larger number of pulmonary metastases. CT was also useful in revealing unsuspected local recurrences in four of 18 patients although one false positive diagnosis was made. Overall, the information provided by CT altered the clinical management in 18 patients (23%); the most important change was that surgery was avoided. Computed tomography should be regarded as the investigation of choice for the assessment of the primary or locally recurrent tumour and the detection of "occult" pulmonary metastases.
1977年至1981年间,77例软组织肉瘤患者接受了计算机断层扫描(CT)检查。对结果进行了分析,以确定这些肿瘤在CT上的特征、CT预测可切除性和检测远处转移的准确性,以及CT检查结果对患者治疗的影响。大多数肿瘤表现为肿块,其边界清晰,要么是由于周围软组织平面的衬托,要么是因为肿瘤与周围组织的衰减值有显著差异。CT表现与肿瘤组织学之间未发现相关性。将基于CT表现的可操作性预测与24例患者的手术结果进行了比较。该预测在22例患者(92%)中正确,并且在11例患者(46%)中提供了进一步有用的手术信息。将CT检查结果与胸部X线检查结果(包括全肺断层扫描)进行比较,结果显示CT发现的肺转移瘤数量明显更多。CT还有助于发现18例患者中有4例未被怀疑的局部复发,尽管有1例假阳性诊断。总体而言,CT提供的信息改变了18例患者(23%)的临床治疗;最重要的改变是避免了手术。计算机断层扫描应被视为评估原发性或局部复发性肿瘤以及检测“隐匿性”肺转移瘤的首选检查方法。