染发剂的使用与膀胱癌风险

Use of hair dyes and risk of bladder cancer.

作者信息

Hartge P, Hoover R, Altman R, Austin D F, Cantor K P, Child M A, Key C R, Mason T J, Marrett L D, Myers M H, Narayana A S, Silverman D T, Sullivan J W, Swanson G M, Thomas D B, West D W

出版信息

Cancer Res. 1982 Nov;42(11):4784-7.

PMID:7127313

Abstract

The relation between use of hair dyes and risk of bladder cancer was assessed using data from a case-control study of bladder cancer. Incident cases (2982) and general population controls (5782) were interviewed. The overall estimate of relative risk of bladder cancer for users of hair dyes was 1.0 (95%) confidence interval, 0.9 to 1.2) compared to nonusers. No consistent pattern of association was detected between bladder cancer risk and various indices of timing or intensity of exposure to hair dyes. Various explanations of the lack of association are discussed.

摘要

利用一项膀胱癌病例对照研究的数据，评估了使用染发剂与患膀胱癌风险之间的关系。对2982例新发病例和5782名普通人群对照进行了访谈。与未使用染发剂的人相比，染发剂使用者患膀胱癌的相对风险总体估计值为1.0（95%置信区间为0.9至1.2）。未发现膀胱癌风险与染发剂接触时间或强度的各种指标之间存在一致的关联模式。文中讨论了缺乏关联的各种解释。