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银鲛(Chimaera monstrosa)脑毛细血管的超微结构

The ultrastructure of cerebral blood capillaries in the ratfish, Chimaera monstrosa.

作者信息

Bundgaard M

出版信息

Cell Tissue Res. 1982;226(1):145-54. doi: 10.1007/BF00217089.

DOI:10.1007/BF00217089
PMID:7127416
Abstract

Sharks and skates (Chondrichthyes: Elasmobranchii) have a glial blood-brain barrier, while all other vertebrates examined so far have an endothelial barrier. For comparative reasons it is desirable to examine the blood-brain barrier in species from the other subclass of cartilaginous fish, the holocephalans. The ultrastructure of cerebral capillaries in the chimaera (Chondrichthyes: Holocephali) is described in the present study. The endothelial cells are remarkably thick. Fenestrae and transendothelial channels were not observed. The endothelial cells are joined by elaborate tight junctions. The perivascular glial processes are separated by wide spaces (15-60 nm) without obliterating junctional complexes. These findings indicate that the chimaera has an endothelial blood-brain barrier.

摘要

鲨鱼和鳐鱼(软骨鱼纲:板鳃亚纲)具有神经胶质血脑屏障,而迄今为止所研究的所有其他脊椎动物都具有内皮屏障。出于比较的原因,有必要研究软骨鱼另一亚纲全头亚纲物种的血脑屏障。本研究描述了银鲛(软骨鱼纲:全头亚纲)脑毛细血管的超微结构。内皮细胞非常厚。未观察到窗孔和跨内皮通道。内皮细胞通过精细的紧密连接相连。血管周围的神经胶质突起被宽阔的间隙(15 - 60纳米)隔开,而连接复合体未被破坏。这些发现表明银鲛具有内皮血脑屏障。

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The ultrastructure of cerebral blood capillaries in the ratfish, Chimaera monstrosa.银鲛(Chimaera monstrosa)脑毛细血管的超微结构
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引用本文的文献

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Form and Function of the Vertebrate and Invertebrate Blood-Brain Barriers.脊椎动物和无脊椎动物血脑屏障的形态和功能。
Int J Mol Sci. 2021 Nov 9;22(22):12111. doi: 10.3390/ijms222212111.

本文引用的文献

1
Impermeability of hagfish cerebral capillaries to radio-labelled polyethylene glycols and to microperoxidase.盲鳗脑毛细血管对放射性标记的聚乙二醇和微过氧化物酶的不渗透性。
Brain Res. 1981 Feb 9;206(1):71-81. doi: 10.1016/0006-8993(81)90101-3.
2
Definitive evidence for the existence of tight junctions in invertebrates.无脊椎动物中紧密连接存在的确凿证据。
J Cell Biol. 1980 Sep;86(3):765-74. doi: 10.1083/jcb.86.3.765.
3
A glial blood-brain barrier in elasmobranchs.软骨鱼类中的胶质血脑屏障。
Brain Res. 1981 Dec 7;226(1-2):61-73. doi: 10.1016/0006-8993(81)91083-0.
4
Brain barrier systems in the lamprey. II. Ultrastructure and permeability of the choroid plexus.
Brain Res. 1982 May 20;240(1):65-75. doi: 10.1016/0006-8993(82)90644-8.
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Brain barrier systems in the lamprey. I. Ultrastructure and permeability of cerebral blood vessels.七鳃鳗的脑屏障系统。I. 脑血管的超微结构与通透性。
Brain Res. 1982 May 20;240(1):55-64. doi: 10.1016/0006-8993(82)90643-6.
6
Comparative aspects of blood-brain exchange.血脑交换的比较方面。
Fed Proc. 1980 Dec;39(14):3201-6.
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Transport pathways in capillaries--in search of pores.毛细血管中的转运途径——探寻孔隙
Annu Rev Physiol. 1980;42:325-36. doi: 10.1146/annurev.ph.42.030180.001545.
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Ultrastructure of frog cerebral and pial microvessels and their impermeability to lanthanum ions.青蛙大脑和软脑膜微血管的超微结构及其对镧离子的不渗透性
Brain Res. 1982 Jun 3;241(1):57-65. doi: 10.1016/0006-8993(82)91228-8.
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Electrical resistance of brain microvascular endothelium.脑微血管内皮细胞的电阻
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10
Structural aspects of brain barriers, with special reference to the permeability of the cerebral endothelium and choroidal epithelium.脑屏障的结构方面,特别提及脑内皮和脉络膜上皮的通透性。
Int Rev Cytol. 1980;65:117-91. doi: 10.1016/s0074-7696(08)61960-9.