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佛罗里达州戴德县牙医对成年患者亚急性细菌性心内膜炎的抗生素预防措施

Antibiotic prophylaxis of subacute bacterial endocarditis for adult patients by dentists in Dade County, Florida.

作者信息

Hashway T, Stone L J

出版信息

Circulation. 1982 Nov;66(5):1110-3. doi: 10.1161/01.cir.66.5.1110.

Abstract

To determine compliance with 1977 American Heart Association (AHA) recommendations for antibiotic prophylaxis (AbP) of subacute bacterial endocarditis (SBE), we mailed a questionnaire to 1019 licensed dentists from Dade County, Florida. Of the 614 practicing dentists who responded, 97.7% believe that AbP prevents SBE and 94.2% always obtain a cardiac history from new patients. AbP is given to patients with known rheumatic or other valvular heart disease by 98.9% of responders and to patients with known prosthetic heart valves by 81.5%. The majority of dentists prescribe the antibiotics recommended by the AHA, but the dosage, route, frequency and duration of therapy are usually not according to AHA guidelines. AbP completely consistent with these guidelines is prescribed by 15.4% of dentists for patients with heart disease and by only 6.7% of dentists for patients with prosthetic heart valves. The AHA recommends parenteral AbP for most patients with prosthetic heart valves, but approximately 80% of dentists use only oral agents for these patients. We conclude that most dental patients predisposed to SBE receive AbP, but not in accordance with AHA guidelines. The widest deviation occurs among patients with prosthetic heart valves.

摘要

为确定是否遵守1977年美国心脏协会(AHA)关于亚急性细菌性心内膜炎(SBE)抗生素预防(AbP)的建议,我们向佛罗里达州戴德县的1019名持照牙医邮寄了一份问卷。在回复的614名执业牙医中,97.7%的人认为AbP可预防SBE,94.2%的人总是会询问新患者的心脏病史。98.9%的回复者会给已知患有风湿性或其他瓣膜性心脏病的患者使用AbP,81.5%的回复者会给已知患有人工心脏瓣膜的患者使用AbP。大多数牙医会开出AHA推荐的抗生素,但治疗的剂量、途径、频率和疗程通常不符合AHA指南。15.4%的牙医为心脏病患者开出的AbP完全符合这些指南,而为人工心脏瓣膜患者开出完全符合指南的AbP的牙医仅占6.7%。AHA建议大多数人工心脏瓣膜患者采用胃肠外AbP,但约80%的牙医仅为这些患者使用口服药物。我们得出结论,大多数易患SBE的牙科患者接受了AbP,但不符合AHA指南。人工心脏瓣膜患者的偏差最大。

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