Zindrick M R, Young M P, Daley R J, Light T R
Clin Orthop Relat Res. 1982 Oct(170):219-25.
Metastatic lesions to the bones of the foot occurred in three elderly patients. Biopsy established the diagnosis in a 90-year-old woman. In a 72-year-old man and a 79-year-old man, the diagnosis was possible from roentgenographic features. In the latter, biopsy of an additional osseous metastatic site established the diagnosis. A thorough review of the literature has yielded 72 previously reported cases of metastasis to the foot. Only 38 of these cases were histologically confirmed. Primary tumors of the colon, kidney, and lung are the most common sources of metastasis to the bones of the foot. Metastatic disease should be considered in elderly patients presenting with foot pain and osteolytic lesions, especially when there is a history of a previously diagnosed malignancy. The generally poor prognosis indicates that treatment should be clearly designed to relieve pain.
三名老年患者足部骨骼出现转移性病变。对一名90岁女性进行活检确诊。对一名72岁男性和一名79岁男性,根据X线特征做出诊断。对后者,通过对另一处骨转移部位进行活检确诊。全面回顾文献后发现,此前已有72例足部转移的报道病例。其中只有38例经组织学确诊。足部骨骼转移最常见的原发肿瘤来源是结肠、肾脏和肺部。对于出现足部疼痛和溶骨性病变的老年患者,尤其是有先前确诊恶性肿瘤病史的患者,应考虑转移性疾病。总体预后通常较差,这表明治疗应明确旨在缓解疼痛。