Gall R J, Sim F H, Pritchard D J
Cancer. 1976 Mar;37(3):1492-95. doi: 10.1002/1097-0142(197603)37:3<1492::aid-cncr2820370335>3.0.co;2-q.
Information on lesions that are metastatic to the bones of the feet is limited. Review of the literature revealed only 17 cases, nine of which were confirmed histologically. Our series involved the clinical records, roentgenograms, and pathologic specimens in eight cases of biopsy-proven metastatic involvement of the bones of the foot. In three additional cases, there was clinical and roentgenographic evidence of metastatic osseous foot lesion but biopsy was not done to provide histiolgic confirmation. Genitourinary malignancies tended to be associated with metastasis to the bones of the feet, the calcaneus being the commonest site of involvement. Although metastatic lesions of the foot are rare, foot pain may be suggestive of an occult carcinoma. Foot pain was the initial presenting complaint in five of our eight cases. The pathogenesis of these distal metastatic lesions remains obscure. Specific problems in management are associated with osseous metastases of the foot.
关于转移至足部骨骼的病变的信息有限。文献回顾仅发现17例,其中9例经组织学证实。我们的系列研究涉及8例经活检证实足部骨骼有转移累及的临床记录、X线片和病理标本。另外3例有足部骨骼转移病变的临床和X线证据,但未进行活检以提供组织学证实。泌尿生殖系统恶性肿瘤往往与足部骨骼转移相关,跟骨是最常受累的部位。尽管足部转移病变罕见,但足部疼痛可能提示隐匿性癌。足部疼痛是我们8例患者中5例的首发主诉。这些远端转移病变的发病机制仍不清楚。足部骨转移存在一些特殊的管理问题。