氯化钠溶液中乳酸脱氢酶的H4同工酶——II. ADP-核糖对分子量的影响
H4-isozyme of lactate dehydrogenase in the solution of sodium chloride--II. The effect of ADP-ribose on the molecular weight.
作者信息
Yamamoto S
出版信息
Int J Biochem. 1982;14(10):871-4. doi: 10.1016/0020-711x(82)90066-0.
PMID:7128901
Abstract
- Large tetramer fractions were formed when ADP-ribose was added to H4-isozyme of lactate dehydrogenase. 2. In the presence of ADP-ribose, not only the increase in tetramers was observed but also the existence of octamers and aggregates. 3. The dimer fraction decreased markedly. 4. Two pathways in the formation of aggregates were suggested; one starting from monomers and the other from octamers.
摘要
- 当向乳酸脱氢酶的H4同工酶中添加ADP-核糖时，会形成大量的四聚体组分。2. 在ADP-核糖存在的情况下，不仅观察到四聚体增加，还存在八聚体和聚集体。3. 二聚体组分显著减少。4. 提出了聚集体形成的两条途径；一条从单体开始，另一条从八聚体开始。
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