Kosaka K, Matsushita M, Iizuka R, Mehraein P
Folia Psychiatr Neurol Jpn. 1982;36(2):125-35. doi: 10.1111/j.1440-1819.1982.tb00263.x.
This is a clinico-pathological study of the relationship between Pick's disease and head trauma. Seven of our autopsied cases with Pick's disease had clinical histories and/or neuropathological evidence of a head trauma. Two cases showed no pathological evidence of traumatic brain damage, although they had clinical histories of a head trauma. The other five cases had old contusions located chiefly on the frontal and temporal bases. As far as we know, there is no reported case of Pick's disease with old contusions in the literature. Therefore, our five cases are of great importance to the study of the relationship between Pick's atrophic processes and traumatic brain damage. The conclusion of our study is that traumatic brain damage involving the atrophy centers of Pick's disease or the adjacent regions could evoke or intensify Pick's atrophic processes.
这是一项关于匹克氏病与头部外伤关系的临床病理研究。我们尸检的7例匹克氏病病例有头部外伤的临床病史和/或神经病理学证据。2例虽有头部外伤的临床病史，但无创伤性脑损伤的病理证据。另外5例有陈旧性挫伤，主要位于额叶和颞叶底部。据我们所知，文献中尚无匹克氏病合并陈旧性挫伤的报道。因此，我们的这5例病例对于研究匹克氏萎缩过程与创伤性脑损伤之间的关系具有重要意义。我们的研究结论是，涉及匹克氏病萎缩中心或相邻区域的创伤性脑损伤可引发或加剧匹克氏萎缩过程。
