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腱索断裂外科治疗中的瓣膜修复与置换。二尖瓣功能的术后超声心动图评估。

Valve repair versus replacement in the surgical management of ruptured chordae. A post-operative echocardiographic assessment of mitral valve function.

作者信息

Shore D F, Wong P, Paneth M

出版信息

J Cardiovasc Surg (Torino). 1982 Sep-Oct;23(5):378-82.

PMID:7130258
Abstract

Between January 1971 and December 1978, 74 patients (pts) underwent surgery for ruptured chordae (RC) of the mitral valve. Thirty-eight patients underwent mitral valve replacement and 36 patients underwent repair. The hospital mortality was 8.3% after repair and 7.9% after replacement. Repair was performed by trapezoidal excision of redundant leaflet, re-approximation of the leaflet edges and annuloplasty. At six years the incidence of re-operation after repair was 3% (1/33) and after mitral valve replacement was 14.7% (5/35). The five years survival was 68 +/- 8% after mitral valve replacement and 100% after repair. The incidence of major thrombo-embolic episodes was 0.67 per 100 patient years, without anticoagulation, after repair and 5.7 per 100 patient years, with anticoagulation, following mitral valve replacement. The peak rate of dimension change (PRDC) of the transverse dimension of the left ventricle was determined by echocardiography in 17 patients after repair. The PRDC was within normal range (10/20 cms/sec) in 15 patients, in the stenotic range (10 cms/sec) in 1 patient, and in the regurgitant range (20 cms/sec) in 1 patient. Mitral valve replacement invariably produces PRDC values in the stenotic range. Valve repair is the procedure of choice in ruptured chordae of the posterior leaflet.

摘要

1971年1月至1978年12月期间,74例患者因二尖瓣腱索破裂(RC)接受了手术。38例患者接受了二尖瓣置换术,36例患者接受了修复术。修复术后医院死亡率为8.3%,置换术后为7.9%。修复方法为梯形切除多余瓣叶、重新对合瓣叶边缘和进行瓣环成形术。6年后,修复术后再次手术的发生率为3%(1/33),二尖瓣置换术后为14.7%(5/35)。二尖瓣置换术后5年生存率为68±8%,修复术后为100%。修复术后未进行抗凝时,主要血栓栓塞事件的发生率为每100患者年0.67次,二尖瓣置换术后进行抗凝时为每100患者年5.7次。通过超声心动图测定了17例修复术后患者左心室横径的最大尺寸变化率(PRDC)。15例患者的PRDC在正常范围内(10/20厘米/秒),1例患者在狭窄范围内(10厘米/秒),1例患者在反流范围内(20厘米/秒)。二尖瓣置换术总是会产生狭窄范围内的PRDC值。瓣膜修复是后叶腱索破裂的首选手术方法。

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