Langenskiöld A
J Pediatr Orthop. 1982 Aug;2(3):289-94. doi: 10.1097/01241398-198208000-00009.
A case of osteomyelitis of the femur in a 6-year-old boy, which resulted in pathological fracture of the femoral neck, severe coxa vara deformity, and total sequestration of the diaphysis, is reported. Sequestrectomy was intentionally delayed until 10 months had elapsed from the onset of the disease in order to let an involucrum develop. At removal of the main sequestra, the involucrum was stable and had replaced the necrotic diaphysis. Pseudarthrosis was prevented by the delay of sequestrectomy. During 9 years of growth after the acute stage, the coxa vara deformity spontaneously corrected to a state close to normal anatomy and, at the age of 15 years, the shape of the entire bone was not far from normal. The almost complete restoration to the normal shape of the destroyed femur indicates that both the differentiation capacity of the cells from which it was restored and grew and the guiding forces directing their development had been preserved. Corresponding phenomena, still poorly understood, may play an important role in several pathological conditions of the growing skeleton.
报告了一例6岁男孩股骨骨髓炎病例，该病例导致股骨颈病理性骨折、严重髋内翻畸形以及骨干完全坏死分离。为了让骨痂形成，骨坏死清除术有意推迟至疾病发作10个月后进行。在切除主要坏死骨时，骨痂稳定且已替代坏死的骨干。骨坏死清除术的延迟预防了假关节的形成。在急性期后的9年生长过程中，髋内翻畸形自发矫正至接近正常解剖结构的状态，15岁时，整个骨骼的形状与正常相差不大。被破坏的股骨几乎完全恢复到正常形状，这表明修复和生长所源自的细胞的分化能力以及引导其发育的力量均得以保留。在生长中的骨骼的几种病理状况中，对此仍了解甚少的相应现象可能发挥重要作用。
