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低级别和高级别膀胱肿瘤患者晨尿中尿路上皮细胞的形态计量分析

Morphometrical analysis of urothelial cells in voided urine of patients with low grade and high grade bladder tumours.

作者信息

Ooms E C, Kurver P J, Boon M E

出版信息

J Clin Pathol. 1982 Oct;35(10):1063-5. doi: 10.1136/jcp.35.10.1063.

DOI:10.1136/jcp.35.10.1063
PMID:7130416
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC497883/
Abstract

The morphometric differences between the urothelial cells (wet-fixed Papanicolaoustained) in the voided urine of 2 patients with low grade and high grade bladder tumours were measured. The morphometrical data of this learning set resulted in a cytomorphometrical classification rule, which was applied to a test set of 21 cases with low grade and high grade bladder tumours. The results of the cytomorphometrical classification rule correspond very well with the histomorphometrical classification and the histological grade of the parent tumours. The results indicate that it is feasible to classify bladder tumours using the cytomorphometrical data of the exfoliated urothelial cells alone.

摘要

测量了2例低级别和高级别膀胱肿瘤患者晨尿中尿路上皮细胞(湿固定巴氏染色)的形态计量学差异。该学习集的形态计量学数据得出了一个细胞形态计量学分类规则,并将其应用于21例低级别和高级别膀胱肿瘤病例的测试集。细胞形态计量学分类规则的结果与母肿瘤的组织形态计量学分类和组织学分级非常吻合。结果表明,仅使用脱落尿路上皮细胞的细胞形态计量学数据对膀胱肿瘤进行分类是可行的。

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The reproducibility of cytomorphometrical grading of bladder tumours.
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本文引用的文献

1
Cis-diamminedichloroplatinum (II) in locally advanced and metastatic urothelial cancer.顺二氯二氨合铂(II)治疗局部晚期和转移性尿路上皮癌
Cancer. 1981 Feb 1;47(3):476-80. doi: 10.1002/1097-0142(19810201)47:3<476::aid-cncr2820470309>3.0.co;2-8.
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Clinical evaluation of intraoperative radiotherapy for carcinoma of the urinary bladder.膀胱癌术中放疗的临床评估
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Morphometric differences between urothelial cells in voided urine of patients with grade I and grade II bladder tumours.I级和II级膀胱肿瘤患者晨尿中尿路上皮细胞的形态计量学差异。
J Clin Pathol. 1981 Jun;34(6):612-5. doi: 10.1136/jcp.34.6.612.
4
Quantitative flow-microfluorometric analysis of the DNA in cells from neoplasms of the urinary bladder: correlation of aneuploidy with histological grading and the cytological findings.膀胱肿瘤细胞DNA的定量流式微荧光分析:非整倍体与组织学分级及细胞学检查结果的相关性
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Cancer. 1979 May;43(5):1742-51. doi: 10.1002/1097-0142(197905)43:5<1742::aid-cncr2820430525>3.0.co;2-c.
7
The efficacy of urinary cytology in the detection of urothelial tumours. Sensitivity and specificity of urinary cytology.尿细胞学检查在检测尿路上皮肿瘤中的效能。尿细胞学检查的敏感性和特异性。
Urol Res. 1978;6(1):3-12. doi: 10.1007/BF00257076.