Davids N, Berger R L
J Biochem Biophys Methods. 1982 Aug;6(3):205-17. doi: 10.1016/0165-022x(82)90043-4.
The method described here is a general numerical analysis procedure which has been applied to a heat conduction Batch calorimeter for the deconvolution of its thermograms, and is based on a computer simulation of the heat conduction behavior of the instrument with time. We show by means of test signals that the method can deconvolute the signal with a resolving time that is about two orders of magnitude smaller than the time constant of the calorimeter itself. The method can be applied to time signals generally, provided that the instrument producing them can be simulated.