Davies H A, Jones D B, Rhodes J
JAMA. 1982 Nov 12;248(18):2274-8.
One hundred consecutive medical emergency patients with anterior chest pain were followed to their final diagnosis to discover the prevalence of esophageal disease as the cause of anginal pain. Seventy-seven of the patients had pain that was anginal in character, and one fifth of these (16 patients) had abnormalities demonstrated by the following esophageal investigations: endoscopy with biopsy, manometry, radiology, and acid perfusion. The 16 patients whose anginal pain was thought to be due to esophageal disease all performed normally on an exercise tolerance test, and in eight of them the association between the esophagus and their symptoms was demonstrated by a positive provocation test result: esophageal acid perfusion was the most useful investigation in this group.
对连续100例因前胸疼痛前来就诊的急诊患者进行跟踪直至最终诊断,以发现食管疾病作为心绞痛病因的患病率。其中77例患者有典型的心绞痛疼痛,这些患者中有五分之一(16例)通过以下食管检查显示出异常:内镜检查及活检、测压、放射学检查和酸灌注试验。16例心绞痛被认为是由食管疾病引起的患者在运动耐量试验中均表现正常,其中8例患者通过激发试验阳性证实食管与症状之间存在关联:食管酸灌注试验是该组中最有用的检查。