Rimel R W, Giordani B, Barth J T, Jane J A
Neurosurgery. 1982 Sep;11(3):344-51. doi: 10.1227/00006123-198209000-00002.
We have divided head injury into three categories based on the Glasgow Coma Scale (GCS) (severe, 3-8; moderate, 9-12; and minor, 13-15). In a previous report, we described significant disability after minor head injury. The present report describes 199 patients with moderate head injury, 159 of whom underwent follow-up examinations at 3 months. In contrast to patients with minor head injury, half as many were students (17%) and twice as many were intoxicated (53%). Seventy-five patients were studied with computed tomographic (CT) scanning; 30% of the scans were negative and 31% showed a space-occupying mass. As reported by Gennarelli et al. in patients with severe head injuries, those with moderate head injury and subdural hematoma had a very poor outcome: 65% died or were severely disabled and none made a good recovery as measured by the Glasgow Outcome Scale. At 3 months, 38% of the moderate head injury patients had made a good recovery compared with 75% of the minor head injury patients. Within the good recovery category, however, there was much disability (headache, 93%; memory difficulties, 90%; difficulties with activities of daily living, 87%), and only 7% of the patients were asymptomatic. The Halstead-Reitan Neuropsychological Battery in an unselected subset (n = 32) showed significant deficits on all test measures. Sixty-six per cent of the patients previously employed had not returned to work, compared to 33% of the minor head injury patients. The major predictors of unemployment after minor head injury were premorbid characteristics (age, education, and socio-economic status). In contrast, all predictors in moderate head injury were measures of the severity of injury (length of coma, CT diagnosis, GCS on discharge). We conclude that: (a) moderate head injury, not described previously in the literature, results in mortality and substantial morbidity intermediate between those of severe and minor head injury; (b) unlike minor head injury, the principal predictors of outcome after moderate head injury are measures of the severity of injury; and (c) more attention should be directed to patients with moderate head injury than to those with the most severe injuries, in whom brain damage is probably irreversible and all forms of management have demonstrated little success.
我们根据格拉斯哥昏迷量表(GCS)将头部损伤分为三类(重度,3 - 8分;中度,9 - 12分;轻度,13 - 15分)。在之前的一份报告中,我们描述了轻度头部损伤后出现的严重残疾情况。本报告描述了199例中度头部损伤患者,其中159例在3个月时接受了随访检查。与轻度头部损伤患者相比,学生人数减半(17%),而醉酒者人数翻倍(53%)。75例患者接受了计算机断层扫描(CT);30%的扫描结果为阴性,31%显示有占位性肿块。正如Gennarelli等人在重度头部损伤患者中所报告的那样,中度头部损伤并伴有硬膜下血肿的患者预后非常差:65%死亡或严重残疾,按照格拉斯哥预后量表衡量,无人恢复良好。3个月时,38%的中度头部损伤患者恢复良好,而轻度头部损伤患者的这一比例为75%。然而,在恢复良好的类别中,仍存在许多残疾问题(头痛,93%;记忆困难,90%;日常生活活动困难,87%),只有7%的患者没有症状。在一个未经过挑选的亚组(n = 32)中进行的霍尔斯特德 - 赖坦神经心理成套测验显示,所有测试指标都有显著缺陷。之前有工作的患者中,66%没有重返工作岗位,而轻度头部损伤患者的这一比例为33%。轻度头部损伤后失业的主要预测因素是病前特征(年龄、教育程度和社会经济地位)。相比之下,中度头部损伤的所有预测因素都是损伤严重程度的指标(昏迷时长、CT诊断、出院时的GCS评分)。我们得出以下结论:(a)中度头部损伤,此前文献中未作描述,其导致的死亡率和发病率介于重度和轻度头部损伤之间;(b)与轻度头部损伤不同,中度头部损伤后预后的主要预测因素是损伤严重程度的指标;(c)应给予中度头部损伤患者比最重度损伤患者更多关注,因为重度损伤患者的脑损伤可能不可逆转,且各种治疗方法都成效甚微。