脱氧血红蛋白中铁的立体化学

Stereochemistry of iron in deoxyhaemoglobin.

作者信息

Perutz M F, Hasnain S S, Duke P J, Sessler J L, Hahn J E

出版信息

Ultramicroscopy. 1982;9(1-2):31-6. doi: 10.1016/0304-3991(82)90226-1.

Abstract

The EXAFS of human deoxyhaemoglobin closely resembles that of a synthetic model in which the displacement of the iron from the mean porphyrin plane is 0.426 +/- 0.004 A, similar to the displacement of 0.56 +/- 0.03 A found by single crystal X-ray analysis of deoxyhaemoglobin. We find the same Fe-N of 2.06 +/- 0.01 A distance as Eisenberger et al., but show that the displacement of the iron from the nitrogen plane cannot be calculated from that distance.

摘要

人类脱氧血红蛋白的扩展X射线吸收精细结构（EXAFS）与一种合成模型的EXAFS非常相似，在该合成模型中，铁从平均卟啉平面的位移为0.426±0.004埃，这与通过脱氧血红蛋白单晶X射线分析发现的0.56±0.03埃的位移相似。我们得到了与艾森伯格等人相同的铁 - 氮距离，为2.06±0.01埃，但表明不能从该距离计算铁从氮平面的位移。