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兔自主神经受刺激时颌下腺的血流与分泌

Blood flow and secretion in the submaxillary gland of the rabbit during stimulation of the autonomic nerves.

作者信息

Gjörstrup P

出版信息

Acta Physiol Scand. 1982 May;115(1):91-5. doi: 10.1111/j.1748-1716.1982.tb07049.x.

DOI:10.1111/j.1748-1716.1982.tb07049.x
PMID:7136807
Abstract

The excitation of the chorda-tympani nerve caused a marked increase in the blood flow through the gland and in secretion of saliva; both phenomena had a threshold frequency of around 0.3 Hz and reached a maximum at around 20 Hz, where a 6-fold increase in the blood flow and a salivary secretion of at the most 300 microliters/min were seen. Sympathetic excitation severely retarded the blood flow, which almost ceased at frequencies as low as 3-5 Hz; mostly single shocks of sympathetic stimulation reduced the blood flow through the gland. An on-going parasympathetic activation did not alter the effects of sympathetic stimulation on the blood flow and the parasympathetically produced salivary secretion almost stopped. The experiments support previous results, which have suggested electrical excitation of the sympathetic trunk at or above 2 Hz to cause a vasoconstriction which adversely affects the fluid secretion in the rabbit salivary glands.

摘要

鼓索神经的兴奋导致流经腺体的血流量和唾液分泌显著增加;这两种现象的阈值频率约为0.3Hz,在约20Hz时达到最大值,此时血流量增加6倍,唾液分泌最多为300微升/分钟。交感神经兴奋严重阻碍血流量,在低至3-5Hz的频率下血流量几乎停止;大多数交感神经刺激的单次电击会减少流经腺体的血流量。持续的副交感神经激活不会改变交感神经刺激对血流量的影响,并且副交感神经产生的唾液分泌几乎停止。这些实验支持了先前的结果,即已表明以2Hz或更高频率电刺激交感神经干会导致血管收缩,这对兔唾液腺的液体分泌产生不利影响。

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