Baker S R, Wheeler R H, Medvec B
Arch Otolaryngol. 1982 Nov;108(11):703-8. doi: 10.1001/archotol.1982.00790590025008.
A totally implantable infusion pump (infusaid) has been developed to achieve continuous drug delivery for long periods of time. The recent availability of a dual-catheter totally implantable infusion pump permits the infusion of both external carotid arteries simultaneously. This has obvious advantages for the treatment of extensive tumors of the head and neck that extend across the midline. Likewise, for the first time, unilateral local-regional disease that extends inferiorly beyond the nutrient field of the external carotid artery may be treated with intra-arterial infusion chemotherapy without the need to infuse the common carotid or innominate arteries. Unilateral infusion of the entire head and neck is accomplished by using the dual-catheter pump to infuse both the thyrocervical trunk and the external carotid artery.
一种完全植入式输液泵（英福赛德）已被研发出来，以实现长时间的持续药物输送。最近，一种双导管完全植入式输液泵的问世，使得能够同时对双侧颈外动脉进行输注。这对于治疗跨越中线的广泛头颈部肿瘤具有明显优势。同样，首次可以对向下延伸超出颈外动脉营养区域的单侧局部区域疾病进行动脉内灌注化疗，而无需对颈总动脉或无名动脉进行输注。通过使用双导管泵对甲状腺颈干和颈外动脉进行输注，可实现对整个头颈部的单侧输注。
