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1982年系统性红斑狼疮分类的修订标准。

The 1982 revised criteria for the classification of systemic lupus erythematosus.

作者信息

Tan E M, Cohen A S, Fries J F, Masi A T, McShane D J, Rothfield N F, Schaller J G, Talal N, Winchester R J

出版信息

Arthritis Rheum. 1982 Nov;25(11):1271-7. doi: 10.1002/art.1780251101.

Abstract

The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve disease classification. The 1982 revised criteria include fluorescence antinuclear antibody and antibody to native DNA and Sm antigen. Some criteria involving the same organ systems were aggregated into single criteria. Raynaud's phenomenon and alopecia were not included in the 1982 revised criteria because of low sensitivity and specificity. The new criteria were 96% sensitive and 96% specific when tested with SLE and control patient data gathered from 18 participating clinics. When compared with the 1971 criteria, the 1982 revised criteria showed gains in sensitivity and specificity.

摘要

1971年系统性红斑狼疮(SLE)的初步分类标准得到修订和更新,以纳入新的免疫学知识并改进疾病分类。1982年修订的标准包括荧光抗核抗体、抗天然DNA抗体和抗Sm抗原。一些涉及相同器官系统的标准被合并为单一标准。由于敏感性和特异性较低,雷诺现象和脱发未被纳入1982年修订的标准。使用从18个参与诊所收集的SLE患者和对照患者数据进行测试时,新标准的敏感性为96%,特异性为96%。与1971年的标准相比,1982年修订的标准在敏感性和特异性方面有所提高。

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