Cecchini G, Biasi F, Chiarpotto E, Poli G
Boll Soc Ital Biol Sper. 1982 Sep 30;58(18):1195-8.
The peroxidative breakdown of membrane lipids leads to the production of several compounds with carbonyl functions. Their production has been monitored in rat liver homogenates treated with prooxidant agents namely vitamin C and ADP-Fe2+ complex. Preliminar HPLC separation of the unpolar and medium polar carbonyls produced, allowed the identification of few of them, in particular, hexanal and 4-OH-nonenal. The aim of this report is to underline the usefulness to integrate malonaldehyde evaluation with the analysis of the other carbonyls produced during lipid peroxidation.
膜脂的过氧化分解会导致产生几种具有羰基功能的化合物。在用促氧化剂即维生素C和ADP-Fe2+复合物处理的大鼠肝脏匀浆中监测了它们的产生情况。对产生的非极性和中等极性羰基化合物进行初步的HPLC分离，使得能够鉴定出其中的少数几种，特别是己醛和4-羟基壬烯醛。本报告的目的是强调将丙二醛评估与脂质过氧化过程中产生的其他羰基化合物分析相结合的有用性。
