Durand D, Dalle M, Barlet J P
Biol Neonate. 1982;42(3-4):120-6. doi: 10.1159/000241585.
In pregnant guinea pigs on day 60 of gestation, maternal hypercalcemia induced by calcium infusion (10 mg Ca/kg body weight/h, during 2 h) had no significant effect on the fetal plasma calcium level. By contrast, on day 66 of gestation the same infusion of calcium into the pregnant female induced a significant rise both in maternal and fetal plasma calcium levels. This difference might be related to the variations in the efficiency of placental calcium transfer occurring during the last days of gestation in the guinea pig. Plasma calcium, phosphate and magnesium levels decrease during the 12 h following birth in suckling guinea pigs. Plasma calcium and magnesium concentrations returned to normal values at 24 h while plasma phosphate levels increased during the first week of postnatal life.
在妊娠60天的怀孕豚鼠中，通过输注钙（10毫克钙/千克体重/小时，持续2小时）诱导的母体高钙血症对胎儿血浆钙水平没有显著影响。相比之下，在妊娠66天时，向怀孕母鼠输注相同剂量的钙会导致母体和胎儿血浆钙水平显著升高。这种差异可能与豚鼠妊娠最后几天胎盘钙转运效率的变化有关。哺乳豚鼠出生后的12小时内，血浆钙、磷和镁水平会下降。血浆钙和镁浓度在24小时时恢复到正常水平，而血浆磷水平在出生后的第一周内会升高。
