Moore C E, Dhopeshwarkar G A
Biol Neonate. 1982;42(3-4):138-44. doi: 10.1159/000241587.
Differences in positional incorporation of trans and cis isomers of octadecenoic and octadecadienoic acids in placental lecithin of rats was demonstrated. A 14C-labeled albumin complex of elaidic, oleic, linoelaidic, or linoleic acid was injected into the jugular vein of pregnant rats. 6 h later 45-64% of the total radioactivity in placental lipids was found in phospholipids (PL), with a major portion of the label incorporated into choline phosphoglycerides (CPC). Following hydrolysis of placental CPC by phospholipase A2, distribution of radioactivity within isolated fatty acids and lysolecithin suggested preferential incorporation of t,t-18:2 at position 2 and a nearly equal distribution of t-18:1 at positions 1 and 2.
已证实大鼠胎盘卵磷脂中十八碳烯酸和十八碳二烯酸的反式和顺式异构体在位置掺入上存在差异。将14C标记的反油酸、油酸、反亚油酸或亚油酸白蛋白复合物注入妊娠大鼠的颈静脉。6小时后，胎盘脂质中总放射性的45 - 64%存在于磷脂（PL）中，其中大部分标记物掺入胆碱磷酸甘油酯（CPC）中。用磷脂酶A2水解胎盘CPC后，分离出的脂肪酸和溶血卵磷脂中放射性的分布表明，t,t - 18:2优先掺入2位，而t - 18:1在1位和2位的分布几乎相等。
