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胰腺分裂症患者的胰腺炎切除术

Resection for pancreatitis in patients with pancreas divisum.

作者信息

Blair A J, Russell C G, Cotton P B

出版信息

Ann Surg. 1984 Nov;200(5):590-4. doi: 10.1097/00000658-198411000-00006.

DOI:10.1097/00000658-198411000-00006
PMID:6385880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1250541/
Abstract

Pancreas divisum is an anatomic duct variant, which may predispose to pancreatitis. Most patients are managed conservatively, but some patients justify attempts to improve drainage. The correct surgical approach is not yet established, and there has been no series published concerning pancreatic resection in this context. A 6-year experience with resection performed in 14 patients with severe pain is reported. There were no operative deaths, and 11 patients had good pain relief; steatorrhea developed in two patients and diabetes in one. The hypothesis that pancreas divisum may cause pancreatitis is supported by examination of resection specimens after pancreaticoduodenectomy; the dorsal part showed chronic pancreatitis and the ventral portion was normal.

摘要

胰腺分裂是一种解剖学上的导管变异,可能易引发胰腺炎。大多数患者采用保守治疗,但部分患者有必要尝试改善引流。目前尚未确立正确的手术方法,且在此背景下尚无关于胰腺切除术的系列报道。本文报告了对14例剧痛患者进行切除术的6年经验。无手术死亡病例,11例患者疼痛得到良好缓解;2例患者出现脂肪泻,1例患者出现糖尿病。胰十二指肠切除术后对切除标本的检查支持了胰腺分裂可能导致胰腺炎的假说;背侧部分显示为慢性胰腺炎,腹侧部分正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c708/1250541/04ea1bd0dcb5/annsurg00117-0043-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c708/1250541/3632cb597cc9/annsurg00117-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c708/1250541/f74920d16ce0/annsurg00117-0042-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c708/1250541/04ea1bd0dcb5/annsurg00117-0043-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c708/1250541/3632cb597cc9/annsurg00117-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c708/1250541/f74920d16ce0/annsurg00117-0042-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c708/1250541/04ea1bd0dcb5/annsurg00117-0043-a.jpg

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引用本文的文献

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Pancreas divisum: a cause of idiopathic acute pancreatitis.胰腺分裂:特发性急性胰腺炎的一个病因。
CMAJ. 2009 Apr 28;180(9):949-51. doi: 10.1503/cmaj.080446.
3
Surgery for pancreas divisum.胰腺分裂症的手术治疗。

本文引用的文献

1
On the excretory ducts of the pancreas in man, with special reference to their relations to each other, to the common bile duct and to the duodenum.关于人体胰腺的排泄管,特别涉及其相互之间的关系、与胆总管以及与十二指肠的关系。
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New clinical aspects of pancreas divisum.胰腺分裂症的新临床特点
Gastrointest Endosc. 1980 Nov;26(4):143-6. doi: 10.1016/s0016-5107(80)73305-9.
5
Congenital anomaly of pancreas divisum as cause of obstructive pain and pancreatitis.胰腺分裂的先天性异常作为梗阻性疼痛和胰腺炎的病因
Gut. 1980 Feb;21(2):105-14. doi: 10.1136/gut.21.2.105.
6
Surgical treatment of chronic pancreatitis. A review after a ten-year experience.慢性胰腺炎的外科治疗。十年经验回顾。
Arch Surg. 1980 Apr;115(4):545-51. doi: 10.1001/archsurg.1980.01380040167030.
7
Surgical therapy for chronic pancreatitis: selecting the appropriate approach.
Am J Surg. 1981 Dec;142(6):654-9. doi: 10.1016/0002-9610(81)90305-6.
8
Treatment of pancreatitis associated with pancreas divisum by dorsal duct sphincterotomy alone.单纯经背侧胰管括约肌切开术治疗胰腺分裂症相关胰腺炎
Can J Surg. 1982 Nov;25(6):622-6.
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Clinico-pathological conditions associated with pancreas divisum.与胰腺分裂相关的临床病理情况。
Digestion. 1982;23(1):1-8. doi: 10.1159/000198689.
10
Surgical management of pancreas divisum.胰腺分裂症的外科治疗
Am J Surg. 1982 Jan;143(1):107-12. doi: 10.1016/0002-9610(82)90138-6.