Weinberg C, Ilfeld F W, Rosen V, August W, Baddorf R L
Clin Orthop Relat Res. 1982 Nov-Dec(171):256-63.
In two-month-old rabbits, consistent reading with freshly prepared silver-silver chloride electrodes using a glass tube with an ionic transfer plug and a solution of KCl saturated with AgCl disclosed an intramedullary metaphyseal voltage of 1.5-9.0 mV. The proximal metaphysis was positive. Histologic studies of the reaction to implanted constant direct current of 7.5, 15.0 and 30.0 mA suggest the presence of an intramedullary current, with the polarity of the proximal metaphysis negative. There was an osteogenic response to the electrodes in all of the animals. The effect of adjacent muscle on intramedullary current requires further investigation. The effect of normally occurring intramedullary current on dummy electrodes in the process of fracture healing warrants more study.
在两个月大的兔子身上，使用带有离子转移塞的玻璃管和饱和AgCl的KCl溶液，用新制备的银 - 氯化银电极持续读数，发现骨髓干骺端电压为1.5 - 9.0 mV。近端干骺端呈阳性。对植入7.5、15.0和30.0 mA恒定直流电的反应进行组织学研究表明存在髓内电流，近端干骺端的极性为负。所有动物对电极都有骨生成反应。相邻肌肉对髓内电流的影响需要进一步研究。骨折愈合过程中正常出现的髓内电流对虚拟电极的影响值得更多研究。
