Sekiya T, Meller S T, Cosgrove D O, McCready V R
Clin Radiol. 1982 Nov;33(6):635-9. doi: 10.1016/s0009-9260(82)80390-5.
Ultrasound findings of 39 spleens and 68 livers in which histology was obtained at laparotomy or autopsy within a month of the examination and four livers in which abnormalities were found clinically by other methods during long-term follow-up were reviewed to evaluate the various sonographic appearances and the accuracy in detecting involvement of the spleen and liver. Only one out of 17 positive spleens had definite ultrasonic focal lesions. Not only small splenic Hodgkin's foci but also larger ones were overlooked. Of 10 positive livers, six showed diffuse inhomogeneity throughout the liver, two showed multiple, well-defined, echo-poor lesions but two showed no significant ultrasonic abnormality even in retrospect. No correlation was found between the type of Hodgkin's disease and the ultrasonic appearance of involved livers. Ultrasonic examination, however, could differentiate other liver abnormalities, such as fatty changes, a cyst and a thrombosed haemangioma from infiltration of Hodgkin's disease. In one case, splenic lesions became echogenic following-chemotherapy.
对39个脾脏和68个肝脏的超声检查结果进行了回顾，这些脾脏和肝脏在检查后一个月内通过剖腹手术或尸检获得了组织学结果，还有4个肝脏在长期随访中通过其他方法在临床上发现了异常，以评估各种超声表现以及检测脾脏和肝脏受累的准确性。17个阳性脾脏中只有1个有明确的超声局灶性病变。不仅小的脾脏霍奇金病灶被忽视，大的病灶也被忽视。在10个阳性肝脏中，6个显示肝脏弥漫性不均匀，2个显示多个边界清晰的低回声病灶，但2个即使回顾性检查也未发现明显的超声异常。未发现霍奇金病的类型与受累肝脏的超声表现之间存在相关性。然而，超声检查可以将其他肝脏异常，如脂肪变性、囊肿和血栓形成的血管瘤与霍奇金病浸润区分开来。在1例中，化疗后脾脏病变变为高回声。
