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Microsomal metabolism of benzene to species irreversibly binding to microsomal protein and effects of modifications of this metabolism.

作者信息

Tunek A, Platt K L, Bentley P, Oesch F

出版信息

Mol Pharmacol. 1978 Sep;14(5):920-9.

PMID:714029
Abstract
摘要

相似文献

1
Microsomal metabolism of benzene to species irreversibly binding to microsomal protein and effects of modifications of this metabolism.苯的微粒体代谢生成与微粒体蛋白不可逆结合的物质以及这种代谢修饰的影响。
Mol Pharmacol. 1978 Sep;14(5):920-9.
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Mechanism of microsomal metabolism of benzene to phenol.苯微粒体代谢生成苯酚的机制。
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Fluoride stimulation of microsomal benzene metabolism.
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Comparative studies of the in vitro metabolism and covalent binding of 14C-benzene by liver slices and microsomal fraction of mouse, rat, and human.小鼠、大鼠和人类肝脏切片及微粒体部分对14C-苯的体外代谢和共价结合的比较研究。
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Mechanism of covalent adduct formation of diclofenac to rat hepatic microsomal proteins. Retention of the glucuronic acid moiety in the adduct.双氯芬酸与大鼠肝微粒体蛋白形成共价加合物的机制。加合物中葡萄糖醛酸部分的保留。
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Metabolism of benzene in rat hepatocytes. Influence of inducers on phenol glucuronidation.大鼠肝细胞中苯的代谢。诱导剂对苯酚葡萄糖醛酸化的影响。
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Microsomal target proteins of metabolically activated aromatic hydrocarbons.
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Multi-step metabolic activation of benzene in rat liver microsomes.
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Activation of 14C-toluene to covalently binding metabolites by rat liver microsomes.大鼠肝脏微粒体将14C-甲苯激活为共价结合代谢物。
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Relationships between metabolic and non-metabolic susceptibility factors in benzene toxicity.苯毒性的代谢和非代谢易感性因素之间的关系。
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Phase II metabolism of benzene.
苯的Ⅱ相代谢
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Chromosome alterations in peripheral lymphocytes as indices of lifestyle and genotoxicity.外周淋巴细胞中的染色体改变作为生活方式和遗传毒性的指标。
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The toxicology of benzene.苯的毒理学
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Biomonitoring of benzene exposure by trace analyses of phenylguanine.通过苯胍的痕量分析对苯暴露进行生物监测。
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Difference in metabolic profile of potassium canrenoate and spironolactone in the rat: mutagenic metabolites unique to potassium canrenoate.
Arch Toxicol. 1988 Jan;61(3):201-12. doi: 10.1007/BF00316635.
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Multiple-site carcinogenicity of benzene in Fischer 344 rats and B6C3F1 mice.苯在Fischer 344大鼠和B6C3F1小鼠中的多部位致癌性。
Environ Health Perspect. 1989 Jul;82:125-63. doi: 10.1289/ehp.8982125.
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Metabolism of benzene and phenol in macrophages in vitro and the inhibition of RNA synthesis by benzene metabolites.
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The toxicity of benzene and its metabolism and molecular pathology in human risk assessment.苯的毒性及其在人体风险评估中的代谢与分子病理学
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