Magdolina A
Morphol Igazsagugyi Orv Sz. 1978 Oct;18(4):241-51.
Alterations of the retina caused by ketamin were studied in experiment. After a 60-minutes monoanaesthesia with ketamin ultrastructural changes were observed on the inner members of receptor cells, in the three nuclear layers and in the layer of nerve fibres. Severe damage to the structure of the Müller's glial cells providing nutrition to neural-elements was also revealed. Three days after the anaesthesia beside the regression of these alterations, glycogen deposits could be seen in the Müller's cells. This phenomenon and some side effects caused by ketamin can be explained by increased utilization of oxygen and relative hypoxia.
在实验中研究了氯胺酮引起的视网膜改变。用氯胺酮进行60分钟单次麻醉后，在受体细胞的内部结构、三个核层和神经纤维层观察到超微结构变化。还发现为神经元件提供营养的米勒胶质细胞结构受到严重损伤。麻醉三天后，除了这些改变的消退外，在米勒细胞中可见糖原沉积。这种现象以及氯胺酮引起的一些副作用可以用氧利用增加和相对缺氧来解释。
