Platonov I A, Iasnetsov V S
Farmakol Toksikol. 1982 Sep-Oct;45(5):42-5.
The effect of levomepromazin, propazin, diprazin and dyphenhydramine on the development of traumatic edema of the brain has been studied. Phenothiazine derivatives with an unbranched dialkylaminoalkyl side chain at the nitrogen atom (propazin) have been found to produce the most remarkable antiedematic action. The drugs that have a branched dialkylaminoalkyl chain (levomepromazin, diprazin) do not return brain water content to normal.
已研究了左美丙嗪、丙嗪、地普嗪和苯海拉明对脑创伤性水肿发展的影响。已发现氮原子上带有直链二烷基氨基烷基侧链的吩噻嗪衍生物（丙嗪）具有最显著的抗水肿作用。带有支链二烷基氨基烷基链的药物（左美丙嗪、地普嗪）不能使脑含水量恢复正常。
