Kicovic P M, Franchi F, Luisi M
Reproduccion. 1982 Apr-Jun;6(2):113-6.
To study the effect of 2-hydroxyestrone (2-OHE1) on circulating prolactin (PRL) in a hyperprolactinaemic state, seven anovulatory women with hyperprolactinaemia were given a 2-OHE1 infusion at a rate of 80 microgram/h for 3 h following a control infusion. Plasma samples for PRL determination were obtained at 30-minute intervals for 6h. No changes in PRL levels were observed during the 2-OHE1 infusion as compared with the control period. It was concluded under conditions of the present experiment that 2-OHE1 does not suppress circulating PRL in hyperprolactinaemic anovulatory women.
为研究2-羟雌酮（2-OHE1）对高泌乳素血症状态下循环泌乳素（PRL）的影响，对7名高泌乳素血症的无排卵女性在对照输注后以80微克/小时的速率给予2-OHE1输注，持续3小时。在6小时内每隔30分钟采集血浆样本用于PRL测定。与对照期相比，在2-OHE1输注期间未观察到PRL水平的变化。在本实验条件下得出结论，2-OHE1不会抑制高泌乳素血症的无排卵女性的循环PRL。
