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苏联对环境中N-亚硝基化合物的研究。

Research on environmental N-nitroso compounds in the USSR.

作者信息

Bogovski P, Rooma M, Uibu J, Kann J, Tauts O

出版信息

IARC Sci Publ. 1982(41):259-66.

PMID:7141534
Abstract

Food samples from various parts of the USSR have been analysed for volatile N-nitrosamines (NA). The results are comparable to data published elsewhere. Kilning of malt with direct combustion gases accounts for the presence of NA in beer. NA have been found in city air, diesel exhausts and in a rubber factory. Vulcanized rubber contains NDMA and NMOR. Nitrosoproline has been determined in a variety of foodstuffs. Variations of nitrate contents in vegetables due to mineral fertilizers and some herbicides are reported. A steady increase of average nitrate concentrations in vegetables has been observed in Estonia over a period of 12 years. Precursors of NA have been found in water (Moldavia), and soil (Moscow district and Tshuvash republic). Nitramines can be formed in vivo from NA, and vice versa. Formation of NDMA from aminopyrine has been inhibited under gastric conditions by properly composed meals. Numerous food components have been studied as nitrite scavengers. Modifications of analytical methods for NA have been proposed. Four laboratories in the USSR are equipped with the Thermal Energy Analyzer.

摘要

对苏联各地的食品样本进行了挥发性N-亚硝胺(NA)分析。结果与其他地方发表的数据相当。用直接燃烧气体焙烧麦芽导致啤酒中存在NA。在城市空气、柴油机废气和一家橡胶厂中发现了NA。硫化橡胶含有N-亚硝基二甲胺(NDMA)和N-亚硝基吗啉(NMOR)。已在多种食品中测定了亚硝基脯氨酸。报告了由于矿物肥料和一些除草剂导致蔬菜中硝酸盐含量的变化。在爱沙尼亚,12年来观察到蔬菜中平均硝酸盐浓度稳步上升。在水(摩尔多瓦)和土壤(莫斯科地区和楚瓦什共和国)中发现了NA的前体。硝胺可在体内由NA形成,反之亦然。在胃部条件下,适当搭配的膳食可抑制氨基比林形成NDMA。已对许多食品成分作为亚硝酸盐清除剂进行了研究。已提出对NA分析方法的改进。苏联有四个实验室配备了热能分析仪。

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