英普咪定（SK&F 92676）是一种效力很强且特异性很高的组胺H2受体激动剂。 - Suppr

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超能文献

Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors.

作者信息

Durant G J, Duncan W A, Ganellin C R, Parsons M E, Blakemore R C, Rasmussen A C

出版信息

Nature. 1978 Nov 23;276(5686):403-5. doi: 10.1038/276403a0.

DOI:10.1038/276403a0

PMID:714166

Abstract

摘要

相似文献

Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors.英普咪定（SK&F 92676）是一种效力很强且特异性很高的组胺H2受体激动剂。

Nature. 1978 Nov 23;276(5686):403-5. doi: 10.1038/276403a0.

Impromidine (SK & F 92676) acts as a partial agonist on the isolated whole stomach of the rat.英普咪定（SK&F 92676）对大鼠离体全胃起部分激动剂的作用。

Br J Pharmacol. 1980 May;69(1):6-7. doi: 10.1111/j.1476-5381.1980.tb10874.x.

Gastric secretory studies in humans with impromidine (SK&F 92676)--a specific histamine H2 receptor agonist.使用英普咪定（SK&F 92676）——一种特异性组胺H2受体激动剂，对人体进行胃分泌研究。

Gastroenterology. 1980 Mar;78(3):505-11.

Cardiovascular studies with impromidine (SK&F 92676), a new very potent and specific histamine H2-receptor agonist.使用新型强效特异性组胺H2受体激动剂英普咪定（SK&F 92676）进行的心血管研究。

J Pharm Pharmacol. 1979 Sep;31(9):577-82. doi: 10.1111/j.2042-7158.1979.tb13595.x.

Effect of impromidine (SK&F 92676) on the isolated papillary muscle of the guinea-pig.英普咪定（SK&F 92676）对豚鼠离体乳头肌的作用。

Br J Pharmacol. 1981 Feb;72(2):197-9. doi: 10.1111/j.1476-5381.1981.tb09113.x.

Direct and indirect actions of impromidine (a new H2-receptor agonist) on atrial tissue.

Life Sci. 1981 Aug 24;29(8):817-24. doi: 10.1016/0024-3205(81)90038-2.

Impromidine (SK&F 92676)--a potent and highly selective histamine H2-receptor agonist in man [proceedings].英普咪定（SK&F 92676）——一种对人体强效且高度选择性的组胺H2受体激动剂[会议论文集]

Br J Clin Pharmacol. 1979 Apr;7(4):421P-422P.

Comparison of the agonist activity of impromidine (SK & F 92676) in anaesthetized rabbits and on the rabbit isolated fundic mucosa.在麻醉兔体内及兔离体胃底黏膜上，比较英普咪定（SK & F 92676）的激动剂活性。

Br J Pharmacol. 1981 Aug;73(4):917-9. doi: 10.1111/j.1476-5381.1981.tb08746.x.

Effects of impromidine, a specific H2-receptor agonist and 2(2-pyridyl)-ethylamine, an H1-receptor agonist, on stimulation-induced release of [3H]-noradrenaline in guinea-pig isolated atria.特异性H2受体激动剂英普咪定和H1受体激动剂2-(2-吡啶基)-乙胺对豚鼠离体心房刺激诱导的[3H]-去甲肾上腺素释放的影响。

Br J Pharmacol. 1982 Jun;76(2):305-11. doi: 10.1111/j.1476-5381.1982.tb09221.x.

Histamine H2 receptors and intrinsic factor secretion.组胺H2受体与内因子分泌

Scand J Gastroenterol. 1980;15(3):377-84. doi: 10.3109/00365528009181487.

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Structure-Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands.以开发选择性组胺受体配体为目标的杂芳基丙基胍类化合物的构效关系

ChemistryOpen. 2019 Mar 5;8(3):285-297. doi: 10.1002/open.201900011. eCollection 2019 Mar.

Molecular and cellular analysis of human histamine receptor subtypes.人类组胺受体亚型的分子和细胞分析。

Trends Pharmacol Sci. 2013 Jan;34(1):33-58. doi: 10.1016/j.tips.2012.11.001. Epub 2012 Dec 17.

Point mutations in the second extracellular loop of the histamine H2 receptor do not affect the species-selective activity of guanidine-type agonists.组胺H2受体第二个细胞外环中的点突变不影响胍类激动剂的物种选择性活性。

Naunyn Schmiedebergs Arch Pharmacol. 2007 Dec;376(4):253-64. doi: 10.1007/s00210-007-0204-4. Epub 2007 Nov 13.

In vitro cardiac pharmacology of the new histamine H2-receptor agonist amthamine: comparisons with histamine and dimaprit.新型组胺H2受体激动剂安他明的体外心脏药理学：与组胺和二甲双胍的比较。

Agents Actions. 1993 Sep;40(1-2):44-9. doi: 10.1007/BF01976750.

Immunologic and neuropharmacologic stimulation of mucous glycoprotein release from human airways in vitro.体外对人呼吸道黏液糖蛋白释放的免疫和神经药理学刺激。

J Clin Invest. 1980 Dec;66(6):1400-8. doi: 10.1172/JCI109993.

Proceedings of the British Pharmacological Society. 17th-19th December, 1979: University of London (Institute of Education).英国药理学会会议记录。1979年12月17日至19日：伦敦大学（教育学院）

Br J Pharmacol. 1980 Jun;69(2):265P-346P.

Analysis of histamine receptors in the central thermoregulatory mechanism of Mastomys natalensis.南非多乳鼠中枢体温调节机制中组胺受体的分析

Br J Pharmacol. 1982 Jan;75(1):145-9. doi: 10.1111/j.1476-5381.1982.tb08767.x.

The effect of inhibitors of arachidonic acid metabolism on drug-induced contractions in isolated tracheal smooth muscle of the pig.花生四烯酸代谢抑制剂对猪离体气管平滑肌药物诱导收缩的影响。

Br J Pharmacol. 1982 Jan;75(1):129-36. doi: 10.1111/j.1476-5381.1982.tb08765.x.

Prostaglandin-mediated contractile effect of impromidine and dimaprit in the isolated rat stomach fundus.

Experientia. 1981 Oct 15;37(10):1092-3. doi: 10.1007/BF02085030.

Br J Pharmacol. 1981 Aug;73(4):917-9. doi: 10.1111/j.1476-5381.1981.tb08746.x.

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