Kal H B
Int J Radiat Oncol Biol Phys. 1982 Sep;8(9):1549-54. doi: 10.1016/0360-3016(82)90615-0.
Californium-252, an isotope emitting neutrons, gamma photons and alpha particles, is being investigated for its practical use in interstitial Curie therapy. After an introduction in which the history of Californium-252 and its application in industry are described, a review of results concerning RBE values of Cf-neutrons for tolerance of different types of normal tissues and for responses of experimental tumors as a function of dose rate is given. In addition, a review of clinical results is presented.
锎 - 252是一种能发射中子、γ光子和α粒子的同位素,目前正在研究其在间质居里治疗中的实际应用。在介绍了锎 - 252的历史及其在工业中的应用之后,本文综述了有关锎中子对不同类型正常组织耐受性以及实验性肿瘤反应的相对生物效应(RBE)值随剂量率变化的结果。此外,还介绍了临床结果。