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用于盆腔放疗的锎 Cf-252

Californium Cf-252 for pelvic radiotherapy.

作者信息

Maruyama Y, Feola J M, Tai D, Wilson L C, Van Nagell J R, Yoneda J

出版信息

Oncology. 1978;35(4):172-8. doi: 10.1159/000225280.

DOI:10.1159/000225280
PMID:360128
Abstract

Clinical data about therapy concerning tumors of the female gynecological cancers of the cervix, vagina and uterus are reviewed. Dosimetric, laboratory and radiobiological research data form the basis for an approach to such tumors using Cf-252 as a form of boost brachytherapy. Extreme personnel hazards are a real and important consideration and indicate that maximal containment and isolation procedures should be exercised in its use. But it is anticipated that new possibilities for successful radiotherapy of an important cagegory of tumor will be realised by its clinical evaluation and application.

摘要

本文综述了关于子宫颈、阴道和子宫女性妇科癌症肿瘤治疗的临床数据。剂量学、实验室和放射生物学研究数据构成了使用Cf - 252作为一种后装近距离放射治疗形式来治疗此类肿瘤方法的基础。极端的人员危害是一个现实且重要的考虑因素,这表明在使用它时应采取最大程度的防护和隔离措施。但预计通过其临床评估和应用,将为一类重要肿瘤的成功放射治疗带来新的可能性。

相似文献

1
Californium Cf-252 for pelvic radiotherapy.用于盆腔放疗的锎 Cf-252
Oncology. 1978;35(4):172-8. doi: 10.1159/000225280.
2
Neutron and gamma dose distribution for tandem, tandem and ovoid and plaque for intracavitary 252Cf therapy of cervix carcinoma.
Radiat Med. 1983 Jul-Sep;1(3):230-6.
3
New understanding from Cf brachytherapy trials and considerations for neutron therapy of bulky gyn carcinoma for future.
Strahlenther Onkol. 1994 May;170(5):253-63.
4
Effectiveness of Cf 252-neutrons at low dose rates.低剂量率下 Cf 252 中子的有效性。
Int J Radiat Oncol Biol Phys. 1982 Sep;8(9):1549-54. doi: 10.1016/0360-3016(82)90615-0.
5
[Reoxygenation of tumors of the uterine cervix during combined radiotherapy using low dose gamma-neutron irradiation with californium-252].
Cesk Radiol. 1989 Mar;43(2):125-35.
6
[Dosimetry in intracavitary radiation therapy with 252Cf].
Med Radiol (Mosk). 1979 Aug;24(8):47-50.
7
Therapeutic dosimetry for Cf-252 neutron brachytherapy of pelvic cancer.用于盆腔癌锎 - 252 中子近距离治疗的治疗剂量学
Int J Radiat Oncol Biol Phys. 1985 May;11(5):927-35. doi: 10.1016/0360-3016(85)90115-4.
8
[Principles of dosimetric planning in contact therapy with highly active Cf-252 sources].[高活性 Cf-252 源近距离治疗的剂量学规划原则]
Strahlenther Onkol. 1987 Nov;163(11):742-5.
9
Evaluation of time-dose and fractionation for 252Cf neutrons in preoperative bulky/barrel-cervix carcinoma radiotherapy.
Int J Radiat Oncol Biol Phys. 1990 Dec;19(6):1561-8. doi: 10.1016/0360-3016(90)90373-r.
10
Assessment of neutron/gamma-ray dose ratios in intracavitary 252Cf neutron therapy.腔内 252Cf 中子治疗中中子/γ射线剂量比的评估。
Radiology. 1978 Sep;128(3):795-7. doi: 10.1148/128.3.795.

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RBE of spleen CFU-S to low dose rate Cf-252 neutron or photon radiation.
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