Szulc-Kuberska J, Klimek A
Neurol Neurochir Pol. 1978 Jul-Aug;12(4):409-11.
The authors used lithium carbonate in treatment of 7 patients with Horton's headaches of primarily or secondarily chronic character. In all patients the blood level of lithium was determined and it was found to reach therapeutic levels. Disappearance of attacks was achieved in 3 cases, significant improvement in 2, and in 2 cases treatment was ineffective. The mechanism of lithium action in this disease is discussed. The authors recommend lithium as worthy of use since other drugs are ineffective in this disease or they cannot be used, eg. steroids or indomethacin, in view of frequent coexistence of paptic ulcer.
作者使用碳酸锂治疗7例原发性或继发性慢性霍顿头痛患者。测定了所有患者的血锂水平,发现均达到治疗水平。3例患者发作消失,2例显著改善,2例治疗无效。文中讨论了锂在该疾病中的作用机制。作者推荐使用锂,因为其他药物对该疾病无效或因胃溃疡频繁并存而不能使用,如类固醇或吲哚美辛。