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荧光素二月桂酸酯试验与促胰液素-缩胆囊素试验对胰腺外分泌功能的前瞻性比较。

Prospective comparison of the fluorescein-dilaurate test with the secretin-cholecystokinin test for pancreatic exocrine function.

作者信息

Boyd E J, Cumming J G, Cuschieri A, Wood R A, Wormsley K G

出版信息

J Clin Pathol. 1982 Nov;35(11):1240-3. doi: 10.1136/jcp.35.11.1240.

DOI:10.1136/jcp.35.11.1240
PMID:7142432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC497935/
Abstract

In a prospective study of 60 patients undergoing investigation for possible exocrine pancreatic disease the fluorescein-dilaurate test was compared with the secretin-cholecystokinin (CCK) test. Forty one patients had a normal response to secretin-CCK, 14 patients had abnormal responses and in five patients the results were equivocal. Taking the secretin-CCK test as the diagnostic criterion, the fluorescein-dilaurate test had a sensitivity of 100% and a negative predictive value of 100%. There was a 54% false-positive rate. The fluorescein-dilaurate test is easy to perform and is a useful screening test for pancreatic exocrine insufficiency.

摘要

在一项针对60例可能患有胰腺外分泌疾病而接受检查的患者的前瞻性研究中，将荧光素二月桂酸酯试验与促胰液素-胆囊收缩素（CCK）试验进行了比较。41例患者对促胰液素-CCK试验反应正常，14例患者反应异常，5例患者结果不明确。以促胰液素-CCK试验作为诊断标准，荧光素二月桂酸酯试验的敏感性为100%，阴性预测值为100%。假阳性率为54%。荧光素二月桂酸酯试验操作简便，是一种用于筛查胰腺外分泌功能不全的有用试验。

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本文引用的文献

1
[Pancreolauryl test compared to NBT-PABA test. Screening test for diagnosis of exocrine pancreatic insufficiency?].[与对氨基苯甲酸试验相比，月桂酰胰腺试验。外分泌性胰腺功能不全诊断的筛查试验？]
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The response to infusion of a combination of secretin and pancreozymin in health and disease.健康与疾病状态下对促胰液素和胰酶泌素联合输注的反应。
Scand J Gastroenterol. 1969;4(7):623-32.
3
[Pancreas specificity of the oral function test using fluorescein di-or. monolaurate, respectively].
Verh Dtsch Ges Inn Med. 1971;77:524-6.

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