McCormack L S, Elgart M L, Turner M L
J Am Acad Dermatol. 1982 Nov;7(5):678-80. doi: 10.1016/s0190-9622(82)70151-3.
Benoxaprofen (Opren) is a nonsteroidal anti-inflammatory agent used in the treatment of arthritis. Photosensitivity, including onycholysis, has been reported in the rheumatologic literature. This drug has recently been approved for use in the United States under the name of Oraflex. In order to alert the dermatology community, we report a case of photo-onycholysis which developed in a patient being treated with benoxaprofen and review the data on this drug and its side effects.
苯恶洛芬(奥普伦)是一种用于治疗关节炎的非甾体抗炎药。在风湿病学文献中已报道过包括甲床分离在内的光敏反应。这种药物最近以奥弗拉克斯的名称在美国获批使用。为提醒皮肤科界,我们报告了一例在用苯恶洛芬治疗的患者中发生的光线性甲床分离病例,并回顾了有关该药物及其副作用的数据。